The newest of the new in gene therapy: 'Tag and target and exchange'
A combination of two techniques promises to improve the efficiency and effectiveness of experimental gene therapies, while also reducing potential side effects says a new research report published in...
View ArticleBioinformatics and epigenetics - computer-aided cancer diagnosis
The relatively young research field of epigenetics is the talk of the town. Many scientists expect the research on biochemical modifications beyond the actual DNA strand to lead to huge progress in the...
View ArticleProtein prevents DNA damage in the developing brain and might serve as a...
St. Jude Children's Research Hospital scientists have rewritten the job description of the protein TopBP1 after demonstrating that it guards early brain cells from DNA damage. Such damage might...
View ArticleNutrition tied to improved sperm DNA quality in older men
A new study led by scientists from the Lawrence Berkeley National Laboratory (Berkeley Lab) found that a healthy intake of micronutrients is strongly associated with improved sperm DNA quality in older...
View ArticleTrojan horse drug therapy provides new approach to treating breast cancer
When Linda Tuttle was diagnosed with breast cancer, she never imagined her experience would inspire her colleagues to design new treatments to tackle the disease.
View ArticleImmune cells make flexible choices
Our immune system must be tremendously complex to respond to the unending assault of viruses, bacteria and cancerous cells. One of the mechanisms used by the immune system to cope with the huge variety...
View ArticleAbnormal DNA maintenance related to cancer
DNA, like houses and cars, needs ongoing maintenance. Rays of ultraviolet sunlight, chemical pollutants and normal biochemical processes in the cell can damage it. Cells routinely repair this damage...
View ArticleNew clues in hunt for heredity in type 2 diabetes
Type 2 diabetes has strong hereditary tendencies and the genes we are born with cannot be changed. However, new research from Lund University in Sweden shows that we can modify the function of the...
View ArticleUnique study reveals genetic 'spelling mistakes' that increase the risk of...
More than 80 genetic 'spelling mistakes' that can increase the risk of breast, prostate and ovarian cancer have been found in a large, international research study within the framework of the EU...
View ArticleStudy confirms thirdhand smoke causes DNA damage
(Medical Xpress)—A study led by researchers from Lawrence Berkeley National Laboratory has found for the first time that thirdhand smoke—the noxious residue that clings to virtually all surfaces long...
View ArticleDNA detectives track down nerve disorder cause
Better diagnosis and treatment of a crippling inherited nerve disorder may be just around the corner thanks to an international team that spanned Asia, Europe and the United States. The team had been...
View ArticleScientists build 'mechanically active' DNA material
Artificial muscles and self-propelled goo may be the stuff of Hollywood fiction, but for UC Santa Barbara scientists Omar Saleh and Deborah Fygenson, the reality of it is not that far away. By blending...
View ArticleNew developments reveal a molecule with a promising function in terms of...
Researchers from Inserm and CNRS from the Institute for genetics and molecular and cellular biology (IGBMC) and from the Research Institute at the Strasbourg school of biotechnology (Irebs) have...
View ArticleDNA packaging discovery reveals principles by which CRC mutations may cause...
A new discovery from researchers at Huntsman Cancer Institute (HCI) at the University of Utah concerning a fundamental understanding about how DNA works will produce a "180-degree change in focus" for...
View ArticleThe evolution of human intellect: Human-specific regulation of neuronal genes
A new study published November 20 in the open-access journal PLOS Biology has identified hundreds of small regions of the genome that appear to be uniquely regulated in human neurons. These regulatory...
View ArticleResearchers show how cells' DNA repair machinery can destroy viruses
A team of researchers based at Johns Hopkins has decoded a system that makes certain types of immune cells impervious to HIV infection. The system's two vital components are high levels of a molecule...
View Article3Qs: Supreme Court rules human genes can't be patented
The U.S. Supreme Court ruled in a unanimous decision Thursday that naturally occurring human genes can't be patented. The case centered on Myriad Genetics Inc.'s patents on popular breast and ovarian...
View ArticleMolecular robots can help researchers build more targeted therapeutics
Many drugs such as agents for cancer or autoimmune diseases have nasty side effects because while they kill disease-causing cells, they also affect healthy cells. Now a new study has demonstrated a...
View ArticleStudy monitors DNA breaks and chromosome translocations in real time
(Medical Xpress)—Researchers in the U.S. have developed a new method to study damage to DNA and resultant translocations in living cells.
View ArticleDNA damage may cause amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS)—also known as Lou Gehrig's disease—is a neurodegenerative disease that destroys the neurons that control muscle movement. There is no cure for ALS, which kills most...
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