Gene editing could help tackle cancer and inherited diseases
Gene editing techniques developed in the last five years could help in the battle against cancer and inherited diseases, a University of Exeter scientist says.
View ArticleScientists discover distant DNA working together to affect disease risk
A person's DNA sequence can provide a lot of information about how genes are turned on and off, but new research out of Case Western Reserve University School of Medicine suggests the 3-D structure DNA...
View ArticleMay repairs full of mistakes develop into cancer?
A group of researchers at Osaka University found that if DNA damage response (DDR) does not work when DNA is damaged by radiation, proteins which should be removed remain instead, and a loss of genetic...
View ArticleGene analysis could allow the risk determination for esophageal cancer
A genetic modification in the mucous membrane of the esophagus, the Barrett esophagus, can lead to esophageal cancer. If certain biomarkers are contained in these tissue alterations, so-called miDNA,...
View ArticleDefective telomeres are now being linked to dozens of diseases, including...
Studying telomeres, the structures that protect the ends of chromosomes, has become a key issue in biology. In recent years, not only has their relation to ageing been confirmed; defective telomeres...
View ArticleResearchers find link between neighborhood quality and cellular aging
Regardless of chronological age, people who live in neighborhoods with high crime, noise and vandalism are biologically more than a decade older than those who do not, according to a study led by...
View ArticleStudy illuminates role of cancer drug decitabine in repairing damaged cells
A Purdue University study sheds light on how cell damage is reversed by the cancer drug decitabine and identifies a potential biomarker that could indicate a patient's stage of cancer and response to...
View ArticleNew DNA technique means pointing the finger at the right identical twin just...
DNA profiling (or genetic fingerprinting) has proved a revolutionary tool for forensic investigators as a means to identify potential suspects, exonerate the innocent and convict the guilty. But, like...
View ArticleMechanism by which exposure to vinyl chloride may produce cancerous mutations
In the 1970s, epidemiologists found that workers in factories using vinyl chloride, the key ingredient for PVC plastics, had unusually high rates of a rare form of liver cancer called angiosarcoma.
View ArticleSupercomputing reveals the genetic code of cancer
Cancer researchers must use one of the world's fastest computers to detect which versions of genes are only found in cancer cells. Every form of cancer, even every tumour, has its own distinct variants.
View ArticleLess effective DNA repair process takes over as mice age
As we and other vertebrates age, our DNA accumulates mutations and becomes rearranged, which may result in a variety of age-related illnesses, including cancers. Biologists Vera Gorbunova and Andei...
View ArticleInternational charge on new radiation treatment for cancer
(Medical Xpress)—Imagine a targeted radiation therapy for cancer that could pinpoint and blast away tumors more effectively than traditional methods, with fewer side effects and less damage to...
View ArticleHow a protein "cancer cop" targets UV damage in DNA
Ah, summer. People are outside enjoying the warm weather, swimming, playing, or just soaking up that glorious, skin-damaging, high-energy UV radiation from the sun.
View ArticleResearch shows breast cancer gene affects brain development
(Medical Xpress)—The BRCA1 gene, known for its role in suppressing the growth of breast and ovarian tumors, could be necessary for brain development. In a study appearing in the Proceedings of the...
View ArticleDNA damage may cause amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS)—also known as Lou Gehrig's disease—is a neurodegenerative disease that destroys the neurons that control muscle movement. There is no cure for ALS, which kills most...
View ArticleStudy monitors DNA breaks and chromosome translocations in real time
(Medical Xpress)—Researchers in the U.S. have developed a new method to study damage to DNA and resultant translocations in living cells.
View ArticleMolecular robots can help researchers build more targeted therapeutics
Many drugs such as agents for cancer or autoimmune diseases have nasty side effects because while they kill disease-causing cells, they also affect healthy cells. Now a new study has demonstrated a...
View Article3Qs: Supreme Court rules human genes can't be patented
The U.S. Supreme Court ruled in a unanimous decision Thursday that naturally occurring human genes can't be patented. The case centered on Myriad Genetics Inc.'s patents on popular breast and ovarian...
View ArticleResearchers show how cells' DNA repair machinery can destroy viruses
A team of researchers based at Johns Hopkins has decoded a system that makes certain types of immune cells impervious to HIV infection. The system's two vital components are high levels of a molecule...
View ArticleThe evolution of human intellect: Human-specific regulation of neuronal genes
A new study published November 20 in the open-access journal PLOS Biology has identified hundreds of small regions of the genome that appear to be uniquely regulated in human neurons. These regulatory...
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