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Nutrition tied to improved sperm DNA quality in older men

A new study led by scientists from the Lawrence Berkeley National Laboratory (Berkeley Lab) found that a healthy intake of micronutrients is strongly associated with improved sperm DNA quality in older...

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Trojan horse drug therapy provides new approach to treating breast cancer

When Linda Tuttle was diagnosed with breast cancer, she never imagined her experience would inspire her colleagues to design new treatments to tackle the disease.

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Immune cells make flexible choices

Our immune system must be tremendously complex to respond to the unending assault of viruses, bacteria and cancerous cells. One of the mechanisms used by the immune system to cope with the huge variety...

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Abnormal DNA maintenance related to cancer

DNA, like houses and cars, needs ongoing maintenance. Rays of ultraviolet sunlight, chemical pollutants and normal biochemical processes in the cell can damage it. Cells routinely repair this damage...

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New clues in hunt for heredity in type 2 diabetes

Type 2 diabetes has strong hereditary tendencies and the genes we are born with cannot be changed. However, new research from Lund University in Sweden shows that we can modify the function of the...

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Unique study reveals genetic 'spelling mistakes' that increase the risk of...

More than 80 genetic 'spelling mistakes' that can increase the risk of breast, prostate and ovarian cancer have been found in a large, international research study within the framework of the EU...

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Study confirms thirdhand smoke causes DNA damage

(Medical Xpress)—A study led by researchers from Lawrence Berkeley National Laboratory has found for the first time that thirdhand smoke—the noxious residue that clings to virtually all surfaces long...

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Scientists build 'mechanically active' DNA material

Artificial muscles and self-propelled goo may be the stuff of Hollywood fiction, but for UC Santa Barbara scientists Omar Saleh and Deborah Fygenson, the reality of it is not that far away. By blending...

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New developments reveal a molecule with a promising function in terms of...

Researchers from Inserm and CNRS from the Institute for genetics and molecular and cellular biology (IGBMC) and from the Research Institute at the Strasbourg school of biotechnology (Irebs) have...

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DNA packaging discovery reveals principles by which CRC mutations may cause...

A new discovery from researchers at Huntsman Cancer Institute (HCI) at the University of Utah concerning a fundamental understanding about how DNA works will produce a "180-degree change in focus" for...

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The evolution of human intellect: Human-specific regulation of neuronal genes

A new study published November 20 in the open-access journal PLOS Biology has identified hundreds of small regions of the genome that appear to be uniquely regulated in human neurons. These regulatory...

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Researchers show how cells' DNA repair machinery can destroy viruses

A team of researchers based at Johns Hopkins has decoded a system that makes certain types of immune cells impervious to HIV infection. The system's two vital components are high levels of a molecule...

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3Qs: Supreme Court rules human genes can't be patented

The U.S. Supreme Court ruled in a unanimous decision Thursday that naturally occurring human genes can't be patented. The case centered on Myriad Genetics Inc.'s patents on popular breast and ovarian...

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Molecular robots can help researchers build more targeted therapeutics

Many drugs such as agents for cancer or autoimmune diseases have nasty side effects because while they kill disease-causing cells, they also affect healthy cells. Now a new study has demonstrated a...

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Study monitors DNA breaks and chromosome translocations in real time

(Medical Xpress)—Researchers in the U.S. have developed a new method to study damage to DNA and resultant translocations in living cells.

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DNA damage may cause amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS)—also known as Lou Gehrig's disease—is a neurodegenerative disease that destroys the neurons that control muscle movement. There is no cure for ALS, which kills most...

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Research shows breast cancer gene affects brain development

(Medical Xpress)—The BRCA1 gene, known for its role in suppressing the growth of breast and ovarian tumors, could be necessary for brain development. In a study appearing in the Proceedings of the...

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How a protein "cancer cop" targets UV damage in DNA

Ah, summer. People are outside enjoying the warm weather, swimming, playing, or just soaking up that glorious, skin-damaging, high-energy UV radiation from the sun.

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International charge on new radiation treatment for cancer

(Medical Xpress)—Imagine a targeted radiation therapy for cancer that could pinpoint and blast away tumors more effectively than traditional methods, with fewer side effects and less damage to...

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Less effective DNA repair process takes over as mice age

As we and other vertebrates age, our DNA accumulates mutations and becomes rearranged, which may result in a variety of age-related illnesses, including cancers. Biologists Vera Gorbunova and Andei...

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Supercomputing reveals the genetic code of cancer

Cancer researchers must use one of the world's fastest computers to detect which versions of genes are only found in cancer cells. Every form of cancer, even every tumour, has its own distinct variants.

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Mechanism by which exposure to vinyl chloride may produce cancerous mutations

In the 1970s, epidemiologists found that workers in factories using vinyl chloride, the key ingredient for PVC plastics, had unusually high rates of a rare form of liver cancer called angiosarcoma.

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New DNA technique means pointing the finger at the right identical twin just...

DNA profiling (or genetic fingerprinting) has proved a revolutionary tool for forensic investigators as a means to identify potential suspects, exonerate the innocent and convict the guilty. But, like...

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Study illuminates role of cancer drug decitabine in repairing damaged cells

A Purdue University study sheds light on how cell damage is reversed by the cancer drug decitabine and identifies a potential biomarker that could indicate a patient's stage of cancer and response to...

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Researchers find link between neighborhood quality and cellular aging

Regardless of chronological age, people who live in neighborhoods with high crime, noise and vandalism are biologically more than a decade older than those who do not, according to a study led by...

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Defective telomeres are now being linked to dozens of diseases, including...

Studying telomeres, the structures that protect the ends of chromosomes, has become a key issue in biology. In recent years, not only has their relation to ageing been confirmed; defective telomeres...

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Gene analysis could allow the risk determination for esophageal cancer

A genetic modification in the mucous membrane of the esophagus, the Barrett esophagus, can lead to esophageal cancer. If certain biomarkers are contained in these tissue alterations, so-called miDNA,...

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May repairs full of mistakes develop into cancer?

A group of researchers at Osaka University found that if DNA damage response (DDR) does not work when DNA is damaged by radiation, proteins which should be removed remain instead, and a loss of genetic...

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Scientists discover distant DNA working together to affect disease risk

A person's DNA sequence can provide a lot of information about how genes are turned on and off, but new research out of Case Western Reserve University School of Medicine suggests the 3-D structure DNA...

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Gene editing could help tackle cancer and inherited diseases

Gene editing techniques developed in the last five years could help in the battle against cancer and inherited diseases, a University of Exeter scientist says.

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